Furthermore, sampling temperature at room temperature and 37☌ was investigated, and there was no difference in results obtained. A new reference range for the adult Danish population was established as 1.2-1.5 mPa s at 37☌. The microfluidic-based viscometer performed well, and imprecision was comparable to ReoRox® G2 free oscillation rheometer.
Sampling temperature was investigated by drawing and transporting blood at room temperature and 37☌ and comparing the viscosity between the two sampling methods. The reference range was established for the adult population using EDTA-plasma from 120 healthy blood donors. The microVisc™ viscometer was evaluated for within-run and between-run imprecision and bias using standardized reference material (Paragon controls) and Seronorm™ control material. Here, we investigate the performance of a new microfluidic-based viscometer for clinical use, establish a new reference range to be used with this instrument and determine the importance of sampling temperature.
Plasma viscosity is an important biomarker both in diagnostics and treatment monitoring of plasma cell dyscrasias and other disorders with hyperviscosity syndrome as a clinical manifestation.
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